Hammers Gianluca Scamacca, Alphonse Areola and Manuel Lanzini are all understood to be suffering minor knocks suffering in training and have not been included in the match-day squad in West London.
Maxwel Cornet is still out as he receives specialist treatment in France for his calf, Kurt Zouma is still out after undergoing knee surgery in November but is closing in on a return to the squad with a recent virus putting his return back a week ot two.
Right-back Vladimir Coufal is also absent after picking up a knee injury against Leeds in midweek.
West Ham Academy duo Kamarai Swyer and Divin Mubama, who both started on Friday night and scored for the under-21s against Everton, make the bench.
West Ham United starting team: Lukasz Fabianski; Craig Dawson, Angelo Ogbonna, Nayef Aguerd; Ben Johnson Lucas Paqueta, Declan Rice, Tomas Soucek, Emerson; Jarrod Bowen, Michail Antonio
Substitutes: Darren Randolph, Aaron Cresswell, Thilo Kehrer, Pablo Fornals, Conor Coventry, Flynn Downes, Said Benrahma, Divin Mubama, Kamarai Swyer